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LisdexAmphetamine versus Methylphenidate for pediatric patients with ADHD and type 1 diabetes

This is a multicenter, randomized, open-label, cross-over clinical trial in children and adolescents with ADHD and type 1 diabetes.

The trial will be conducted in four reference pediatric diabetes centers in Poland. Children will be randomized to methylphenidate (long-release capsule, doses 18-36-54 mg) versus lisdexamphetamine (LDX, 30-50-70 mg). Pharmacotherapy will continue for 6 months before switching to alternative medication. The primary endpoint (ADHD symptom severity, Conners 3.0 questionnaire) will be assessed by a blinded investigator.

Project start: 01.11.2021

Project end: 01.11.2026

  • University Clinical Hospital in Opole, Opole, Poland
  • University of Opole, Opole, Poland
  • Medical University of Silesia, Katowice, Poland
  • Medical University of Gdansk, Gdansk, Poland
  • Medical University of Warsaw, Warszawa, Poland
  • Medical University of Lodz, Lodz, Poland
  • Polish Federation for Support for Children and Adolescents with Diabetes, Warszawa, Poland

Medical Research Agency, Polen

Agnieszka Butwicka

Project leader

agnieszka.butwicka@ahus.no
Last updated 11/19/2024